| College Football Week # 4 | ||||
| Thursday, September 22 | ||||
| West Virginia | at | Virginia Tech | ||
| Coastal Carolina | at | Georgia State | ||
| Chattanooga | at | Illinois | ||
| Friday, September 23 | ||||
| Virginia | at | Syracuse | ||
| Saturday, September 24 | ||||
| Arkansas | vs | Texas A&M | ||
| Southwest Classic (SWC) at Arlington TX | ||||
| North Texas | at | Memphis | ||
| Rice | at | Houston | ||
| TCU | at | SMU | ||
| Georgia Tech | at | Central Florida | ||
| South Florida | at | Louisville | ||
| Navy | at | East Carolina | ||
| Indiana | at | Cincinnati | ||
| Massachusetts | at | Temple | ||
| Southern Miss. | at | Tulane | ||
| Tulsa | at | Mississippi | ||
| Florida | at | Tennessee | ||
| Kent State | at | Georgia | ||
| Northern Illinois | at | Kentucky | ||
| Missouri | at | Auburn | ||
| Charlotte | at | South Carolina | ||
| VU-Lynchburg | at | Alabama | ||
| New Mexico | at | LSU | ||
| Bowling Green | at | Mississippi State | ||
| Boston College | at | Florida State | ||
| Clemson | at | Wake Forest | ||
| Connecticut | at | N. C. State | ||
| Duke | at | Kansas | ||
| Middle Tennessee | at | Miami-Florida | ||
| Notre Dame | at | North Carolina | ||
| James Madison | at | Appalachian State | ||
| Ball State | at | Georgia Southern | ||
| Marshall | at | Troy | ||
| Arkansas State | at | Old Dominion | ||
| Louisiana | at | UL - Monroe | ||
| Louisiana Tech | at | South Alabama | ||
| Akron | at | Liberty | ||
| Buffalo | at | Eastern Michigan | ||
| Miami-Ohio | at | Northwestern | ||
| Central Michigan | at | Penn State | ||
| Western Michigan | at | San Jose State | ||
| Toledo | at | San Diego State | ||
| Maryland | at | Michigan | ||
| Minnesota | at | Michigan State | ||
| Wisconsin | at | Ohio State | ||
| Iowa | at | Rutgers | ||
| Florida Atlantic | at | Purdue | ||
| Baylor | at | Iowa State | ||
| Kansas State | at | Oklahoma | ||
| Texas | at | Texas Tech | ||
| Fla. International | at | Western Kentucky | ||
| Boise State | at | Texas - El Paso | ||
| Nevada | at | Air Force | ||
| UNLV | at | Utah State | ||
| Wyoming | at | Brigham Young | ||
| Hawai'i | at | New Mexico State | ||
| Arizona | at | California | ||
| Stanford | at | Washington | ||
| Oregon | at | Washington State | ||
| Southern Cal | at | Oregon State | ||
| UCLA | at | Colorado | ||
| Utah | at | Arizona State | ||
| Rhode Island | at | Pittsburgh | ||
| Fordham | at | Ohio | ||
| Houston Baptist | at | Texas State | ||
| Texas Southern | at | UT - San Antonio | ||
| CS-Sacramento | at | Colorado State | ||
| C. Connecticut St. | at | Albany | ||
| Hampton | at | Delaware | ||
| Elon | at | William & Mary | ||
| Monmouth (NJ) | at | Villanova | ||
| New Hampshire | at | Towson | ||
| Stony Brook | at | Richmond | ||
| Harvard | at | Brown | ||
| Columbia | at | Georgetown | ||
| Yale | at | Cornell | ||
| Dartmouth | at | Sacred Heart | ||
| Lafayette | at | Pennsylvania | ||
| Lehigh | at | Princeton | ||
| Holy Cross | at | Colgate | ||
| Bryant | at | Long Island | ||
| Merrimack | at | Delaware State | ||
| St. Francis (PA) | at | Norfolk State | ||
| Furman | at | Cha'ston Southern | ||
| Mercer | at | Gardner-Webb | ||
| S. Carolina State | at | N. C. A&T | ||
| Prairie View | at | Alabama State | ||
| Alabama A&M | at | Florida A&M | ||
| Ark. - Pine Bluff | at | Alcorn State | ||
| Mississippi Valley | at | Jackson State | ||
| Grambling | at | Bethune-Cookman | ||
| E. Tennessee St. | at | Robert Morris | ||
| Western Carolina | at | Samford | ||
| Wofford | at | Kennesaw State | ||
| Eastern Illinois | at | Murray State | ||
| Lindenwood (MO) | at | UT-Martin | ||
| Central Arkansas | at | SE Missouri St. | ||
| South Dakota St. | at | Missouri State | ||
| Northern Iowa | at | Western Illinois | ||
| North Dakota | at | Southern Illinois | ||
| North Dakota St. | at | South Dakota | ||
| Eastern Kentucky | at | Austin Peay | ||
| Jacksonville State | at | Nicholls | ||
| Tarleton State | at | North Alabama | ||
| Incarnate Word | at | SE Louisiana | ||
| Lamar | at | Northwestern St. | ||
| Utah Tech | at | Southern Utah | ||
| Idaho | at | Northern Arizona | ||
| Idaho State | at | Northern Colorado | ||
| Portland State | at | Montana | ||
| Montana State | at | E. Washington | ||
| Weber State | at | UC-Davis | ||
| Marist | at | Drake | ||
| San Diego | at | Valparaiso | ||
| Davidson | at | Presbyterian | ||
| Morehead State | at | Stetson | ||
| W. New Mexico | at | Abilene Christian | ||
| North American | at | TAMU-Commerce | ||
| Mississippi College | at | McNeese State | ||
| Warner | at | Stephen F. Austin | ||
| Lincoln (CA) | at | St. Thomas (MN) | ||
| VU-Lynchburg | at | N. C. Central | ||