| XII – II | Baylor | Iowa State | Kansas | Kansas State | West Virginia | ||||||||||
| 27-Aug | |||||||||||||||
| 3-Sep | Albany | SE Missouri St. | F | Tennessee Tech | South Dakota | Th | at | Pittsburgh | |||||||
| 10-Sep | at | Brigham Young | at | Iowa | at | West Virginia | Missouri | Kansas | |||||||
| 17-Sep | Texas State | Ohio | at | Houston | Tulane | Towson | |||||||||
| 24-Sep | at | Iowa State | Baylor | Duke | at | Oklahoma | Th | at | Virginia Tech | ||||||
| 1-Oct | Oklahoma St. | at | Kansas | Iowa State | Texas Tech | at | Texas | ||||||||
| 8-Oct | Kansas State | TCU | at | Iowa State | |||||||||||
| 15-Oct | Th | at | West Virginia | at | Texas | at | Oklahoma | Th | Baylor | ||||||
| 22-Oct | Kansas | at | Baylor | at | TCU | at | Texas Tech | ||||||||
| 29-Oct | at | Texas Tech | Th | Oklahoma | Oklahoma St. | TCU | |||||||||
| 5-Nov | at | Oklahoma | West Virginia | Oklahoma St. | Texas | at | Iowa State | ||||||||
| 12-Nov | Kansas State | at | Oklahoma St. | at | Texas Tech | at | Baylor | Oklahoma | |||||||
| 19-Nov | TCU | Texas Tech | Texas | at | West Virginia | Kansas State | |||||||||
| 26-Nov | at | Texas | at | TCU | at | Kansas State | Kansas | at | Oklahoma St. | ||||||
| 3-Dec | |||||||||||||||
| ColorCodes | Conference Game | NonConf vs "P5 + 1" | vs other FBS (I-A) | vs FCS (I-AA) | Homecoming | ||||||||||
| XII – II | Oklahoma | Oklahoma State | Texas | Texas Tech | Texas Christian | ||||||||||
| 27-Aug | |||||||||||||||
| 3-Sep | Texas - El Paso | Th | Central Mich. | UL - Monroe | Murray State | F | at | Colorado | |||||||
| 10-Sep | Kent State | Arizona State | Alabama | Houston | Tarleton State | ||||||||||
| 17-Sep | at | Nebraska | Ark. - Pine Bluff | San Antonio | at | N. C. State | |||||||||
| 24-Sep | Kansas State | at | Texas Tech | Texas | at | SMU | |||||||||
| 1-Oct | at | TCU | at | Baylor | West Virginia | at | Kansas State | Oklahoma | |||||||
| 8-Oct | vs | Texas | Texas Tech | vs | Oklahoma | at | Oklahoma St. | at | Kansas | ||||||
| 15-Oct | Kansas | at | TCU | Iowa State | Oklahoma St. | ||||||||||
| 22-Oct | Texas | at | Oklahoma St. | West Virginia | Kansas State | ||||||||||
| 29-Oct | Th | at | Iowa State | at | Kansas State | Baylor | at | West Virginia | |||||||
| 5-Nov | Baylor | at | Kansas | at | Kansas State | at | TCU | Texas Tech | |||||||
| 12-Nov | at | West Virginia | Iowa State | TCU | Kansas | at | Texas | ||||||||
| 19-Nov | Oklahoma St. | at | Oklahoma | at | Kansas | at | Iowa State | at | Baylor | ||||||
| 26-Nov | at | Texas Tech | West Virginia | Baylor | Oklahoma | Iowa State | |||||||||
| 3-Dec | |||||||||||||||