| College Football Week # 4 | ||||
| Thursday, September 21 | ||||
| Georgia State | at | Coastal Carolina | ||
| Friday, September 22 | ||||
| N. C. State | at | Virginia | ||
| Boise State | at | San Diego State | ||
| Saturday, September 23 | ||||
| Memphis | vs | Missouri | ||
| at Saint Louis | ||||
| Charlotte | at | Florida | ||
| UAB | at | Georgia | ||
| Kentucky | at | Vanderbilt | ||
| Mississippi State | at | South Carolina | ||
| UT - San Antonio | at | Tennessee | ||
| Mississippi | at | Alabama | ||
| Arkansas | at | LSU | ||
| Auburn | at | Texas A&M | ||
| Rice | at | South Florida | ||
| SMU | at | TCU | ||
| Miami-Florida | at | Temple | ||
| Tulsa | at | Northern Illinois | ||
| Florida Atlantic | at | Illinois | ||
| Boston College | at | Louisville | ||
| Florida State | at | Clemson | ||
| Army | at | Syracuse | ||
| Georgia Tech | at | Wake Forest | ||
| Duke | at | Connecticut | ||
| North Carolina | at | Pittsburgh | ||
| Virginia Tech | at | Marshall | ||
| Appalachian State | at | Wyoming | ||
| Georgia Southern | at | Ball State | ||
| James Madison | at | Utah State | ||
| Southern Miss. | at | Arkansas State | ||
| Buffalo | at | Louisiana | ||
| Central Michigan | at | South Alabama | ||
| Nevada | at | Texas State | ||
| Western Kentucky | at | Troy | ||
| Akron | at | Indiana | ||
| Maryland | at | Michigan State | ||
| Rutgers | at | Michigan | ||
| Ohio State | at | Notre Dame | ||
| Iowa | at | Penn State | ||
| Minnesota | at | Northwestern | ||
| Louisiana Tech | at | Nebraska | ||
| Wisconsin | at | Purdue | ||
| Ohio | at | Bowling Green | ||
| Kent State | at | Fresno State | ||
| Eastern Michigan | at | Jacksonville State | ||
| Western Michigan | at | Toledo | ||
| Texas | at | Baylor | ||
| Oklahoma State | at | Iowa State | ||
| Brigham Young | at | Kansas | ||
| Central Florida | at | Kansas State | ||
| Texas Tech | at | West Virginia | ||
| Oklahoma | at | Cincinnati | ||
| Sam Houston St. | at | Houston | ||
| Colorado State | at | Middle Tennessee | ||
| UNLV | at | Texas - El Paso | ||
| New Mexico State | at | Hawai'i | ||
| Air Force | at | San Jose State | ||
| New Mexico | at | Massachusetts | ||
| California | at | Washington | ||
| Arizona | at | Stanford | ||
| Colorado | at | Oregon | ||
| Southern Cal | at | Arizona State | ||
| UCLA | at | Utah | ||
| Oregon State | at | Washington State | ||
| Gardner-Webb | at | East Carolina | ||
| Nicholls | at | Tulane | ||
| TAMU-Commerce | at | Old Dominion | ||
| Delaware State | at | Miami-Ohio | ||
| Albany | at | Morgan State | ||
| Elon | at | Campbell | ||
| New Hampshire | at | Delaware | ||
| Maine | at | William & Mary | ||
| Monmouth (NJ) | at | Lafayette | ||
| Rhode Island | at | Villanova | ||
| Richmond | at | Stony Brook | ||
| Norfolk State | at | Towson | ||
| Brown | at | Harvard | ||
| Pennsylvania | at | Bucknell | ||
| Bryant | at | Princeton | ||
| Cornell | at | Yale | ||
| Colgate | at | Holy Cross | ||
| Stonehill | at | Fordham | ||
| Georgetown | at | Columbia | ||
| Lehigh | at | Dartmouth | ||
| Merrimack | at | Wagner | ||
| Sacred Heart | at | St. Francis (PA) | ||
| The Citadel | at | Chattanooga | ||
| Chattanooga | at | Samford | ||
| Mercer | at | Furman | ||
| Wofford | at | Virginia Military | ||
| Cha'ston Southern | at | Western Carolina | ||
| McNeese State | at | Eastern Illinois | ||
| Lindenwood (MO) | at | Illinois State | ||
| SE Missouri St. | at | Eastern Kentucky | ||
| Kennesaw State | at | Tennessee Tech | ||
| UT-Martin | at | North Alabama | ||
| Alabama State | at | Florida A&M | ||
| Ark. - Pine Bluff | at | Alabama A&M | ||
| Prairie View | at | Alcorn State | ||
| Bethune-Cookman | at | Jackson State | ||
| Texas Southern | at | Grambling | ||
| Austin Peay | at | Stephen F. Austin | ||
| Abilene Christian | at | Central Arkansas | ||
| Utah Tech | at | Missouri State | ||
| Western Illinois | at | Southern Utah | ||
| Houston Christian | at | SE Louisiana | ||
| CS-Sacramento | at | Idaho | ||
| Northern Colorado | at | Idaho State | ||
| Montana | at | Northern Arizona | ||
| Montana State | at | Weber State | ||
| E. Washington | at | UC-Davis | ||
| Cal Poly | at | Portland State | ||
| Butler | at | Stetson | ||
| Dayton | at | San Diego | ||
| Marist | at | Valparaiso | ||
| Morehead State | at | St. Thomas (MN) | ||
| N. C. Central | vs | Mississippi Valley | ||
| Circle City Classic at Indianapolis | ||||
| Saint Andrew's | at | Davidson | ||
| SW Baptist | at | Tarleton State | ||
| North American | at | Incarnate Word | ||
| Lincoln (CA) | at | Lamar | ||
| VU-Lynchburg | at | Robert Morris | ||